94944-10-2

Usage

Uses

Used in Pharmaceutical Industry:
(3R,4R)-4-Benzoyloxy-3-(1-tert-butyldimethlsilyloxy]ethyl)azetidin-2-one is used as a potential pharmaceutical agent for its possible biological activities. The presence of the benzoyloxy and tert-butyldimethylsilyloxy groups may enhance its stability and interaction with biological targets, making it a candidate for further research and development in drug discovery.
Used in Material Science:
In the field of material science, (3R,4R)-4-Benzoyloxy-3-(1-tert-butyldimethlsilyloxy]ethyl)azetidin-2-one may be utilized for its unique structural properties. Its potential applications could include the development of new materials with specific characteristics, such as improved stability or reactivity, depending on the outcomes of further research and testing.

Upstream product

• 92686-08-3 <3S-<3α(S^*),4β>>-t-butyl 3-(1-t-butyldimethylsilyloxyethyl)-2-azetidinone-4-carboxylate 
• 85253-97-0 (3S,4S)-3-<(R)-1'-(dimethyl-t-butylsilyloxy)ethyl>-4-oxoazetidine-2-carboxylic acid 
• 94944-08-8 (3S,4S)-4-Benzoyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one 
• 94944-09-9 [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone 
• 93-59-4 Perbenzoic acid 

Downstream Products

• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 
• 107668-59-7 (5R)-selenapenem 
• 107668-55-3 {(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-butylsulfanyl-4-oxo-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 107668-58-6 (E)-2-[(2S,3S)-2-Chloro-3-((R)-1-hydroxy-ethyl)-4-oxo-azetidin-1-yl]-3-methanesulfonyloxy-but-2-enoic acid 4-nitro-benzyl ester 
• 107668-53-1 (E)-2-[(2R,3S)-2-Butylsulfanyl-3-((R)-1-hydroxy-ethyl)-4-oxo-azetidin-1-yl]-3-methanesulfonyloxy-but-2-enoic acid 4-nitro-benzyl ester 
• 107668-57-5 (E)-2-{(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-butylsulfanyl-4-oxo-azetidin-1-yl}-3-methanesulfonyloxy-but-2-enoic acid 4-nitro-benzyl ester 
• 102092-11-5 (2R,3S,5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-methylsulfanyl-3-nitromethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 
• 102562-33-4 (5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-formyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 87408-03-5 (5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-hydroxymethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

METHOD FOR PREPARING 4-ACETOXYAZETIDINONE AND DERIVATIVES THEREOF

The present invention relates to a method for preparing 4-acetoxyazetidinone and derivatives thereof, and in particular to the preparation method comprising the steps of: dissolving a compound which is substituted with a ketone derivative at the C-4 position of beta-lactam in a water soluble organic solvent; and adding a peroxidant, acetic acid salt or an inorganic salt thereto to perform a Baeyer-Villiger oxidation reaction and an acetoxy substitution reaction in a reactor in situ. Thus, according to the preparation method of the present invention, 4-acetoxyazetidinone and derivatives thereof can be easily prepared with high purity and high yield.

Fe2O3-Catalyzed Baeyer-Villiger Oxidation of Ketones with Molecular Oxygen in the Presence of Aldehydes

The Fe2O3-catalyzed oxidation of ketones with molecular oxygen (1 atm) in the presence of an aldehyde at room temperature gives the corresponding lactones or esters highly efficiently.