949557-17-9

Usage

General Description

3-(4-chlorobenzyl)-5-bromopyrimidin-4(3H)-one is a chemical compound with a pyrimidine ring structure that contains a 4-chlorobenzyl group and a 5-bromine substituent. It is a heterocyclic compound with potential use in drug discovery and medicinal chemistry due to its diverse biological activities. It is a reported inhibitor of certain enzymes and receptors, making it a potential candidate for the development of new pharmaceuticals. Its unique structure and properties make it an interesting target for further research in the fields of chemistry and pharmacology.

Upstream product

• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 949557-18-0 3-(4-chlorobenzyl)-5-(4-(benzyloxy)-3-fluorophenyl)pyrimidin-4(3H)-one 

Relevant academic research and scientific papers

Heterobicyclic pyrazole compounds and methods of use

Compounds of Formulas Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting receptor tyrosine kinases and for treating disorders mediated thereby. Methods of using compounds of Formula Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

QUINOLINE COMPOUNDS AND METHODS OF USE

Compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof, are useful for inhibiting receptor tyrosine kinases and for treating hyperproliferative disorders mediated thereby. Methods of using compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. [ Formula I]