949582-47-2Relevant academic research and scientific papers
Synthesis of symmetrical C- and pseudo-symmetrical O-linked disaccharide analogs for arabinosyltransferase inhibitory activity in Mycobacterium tuberculosis
Pathak, Ashish K.,Pathak, Vibha,Riordan, James R.,Suling, William J.,Gurcha, Sudagar S.,Besra, Gurdyal S.,Reynolds, Robert C.
, p. 4527 - 4530 (2008/02/12)
Herein we report the synthesis of symmetrical C-linked and pseudo-symmetrical O-linked disaccharides structurally related to Araf motifs present in the cell wall of MTB. Their activity in a competition-based arabinosyltransferase assay using [14/sup
