949586-96-3Relevant academic research and scientific papers
Novel C2-symmetric chiral ligands: enantioselective transformation of cyclic 1,2-diols into 1,2-bis(phenylsulfenyl) and 1,2-bis(phenylselenyl) derivatives
Wojaczynska, Elzbieta,Skarzewski, Jacek
, p. 593 - 597 (2008/09/19)
Chiral C2-symmetric S,S- and Se,Se-donating ligands as well as the C1 mixed S,Se-donating ligands were prepared from optically active 1,2-cyclohexanediol and 1,2-cyclopentanediol via the respective SN2 reactions. The bis(chalcogen) ligands obtained effectively catalyze the asymmetric allylic alkylation with enantioselectivities of up to 50% ee.
Biocatalytic reduction of a racemic selenocyclohexanone by Brazilian basidiomycetes
Piovan, Leandro,Capelari, Marina,Andrade, Leandro H.,Comasseto, Joao V.,Porto, Andre L.M.
, p. 1398 - 1402 (2008/02/11)
An efficient synthesis of the chiral cyclic secondary alcohols, trans-2-(phenylseleno)cyclohexanol 1a and cis-2-(phenylseleno)cyclohexanol 1a, was obtained by enzymatic reduction of 2-(phenylseleno)cyclohexanone 1 using whole fungal cells. Five strains of white-rot basidiomycetes were examined; Irpex lacteus CCB 196, Pycnoporus sanguineus CCB 196, Trametes rigida CCB 285, Trametes versicolor CCB 202 and Trichaptum byssogenum CCB 203. Cells of T. rigida CCB 285 gave alcohols cis-(RS)-1a and trans-(SS)-1a in high enantiomeric excesses (ca. 99%).
