94968-16-8Relevant academic research and scientific papers
Synthesis and biological evaluation of 3-functionalized 2-phenyl- and 2-alkylbenzo[b]furans as antiproliferative agents against human melanoma cell line
Kwiecień, Halina,Peru?yńska, Magdalena,Stachowicz, Karolina,Piotrowska, Katarzyna,Bujak, Joanna,Kopytko, Patrycja,Dro?dzik, Marek
, (2019/04/29)
The key function of microtubules and mitotic spindle in cell division make them attractive targets in anticancer therapy. In the present study, functionalized in 3 position 2-phenyl- and 2-alkylbenzo[b]furans were synthesized and evaluated as antitumor ag
Benzofuran Systems. Synthesis and Biological Examination of 1-(3-Benzofuranyl)-2-phenylethanones
Kwiecien, Halina,Baumann
, p. 1587 - 1590 (2007/10/03)
Novel 1-(3-benzofuranyl)-2-phenylethanones 4a-d have been prepared by acetylation of 2-alkylbenzofurans 2a-c with phenylacetyl chlorides 3a-b. The methoxy derivatives 4b-d have been demethylated to the corresponding phenols 5b-d with pyridinium hydrochloride. An attempt to obtain the derivatives of 4d and 5a iodinated in the phenyl ring has been undertaken. The novel compounds have been characterized by ir and nmr spectra and their biological activity examined.
