94990-25-7

Basic information

• Product Name: Piperazine, 1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)thioxomethyl]-4-methyl-
• CAS NO: 94990-25-7
• Molecular Formula: C17H22N4S
• Molecular Weight: 314.454
• Mol File: 94990-25-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)thioxomethyl]-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)thioxomethyl]-4-methyl-(94990-25-7)
• EPA Substance Registry System: Piperazine, 1-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)thioxomethyl]-4-methyl-(94990-25-7)

Safety Data

• Hazardous Substances Data: 94990-25-7(Hazardous Substances Data)

Upstream product

• 109-01-3 1-methyl-piperazine 
• 22042-79-1 3,5-dimethyl-1-phenyl-1H-pyrazole-4-carbaldehyde 

Relevant articles and documents

Azoles. 12. Pyrazole carbolic acid thioamides

Morpholids, N-methylpiperazids, piperidids and pyrrolidids of 5-methyl, 3,5-dimethyl-1-phenyl-4-pyrazolthioacetic acid and 3,5-dimethyl-1-phenyl-4-pyrazolcarbonic acid 4-12 are obtained by the Willgerodt-Kindler procedure. The oxothioamids 13-19 result as the intermediate products of the synthesis of thioamids 4-10. The compounds 4, 5, 8, 9, 11, 14 and 17 do not respond to Mycobacterium tuberculosis H37Rv. The thioamids 4, 8 and 11 are of slight toxicity (LD50 greater than 2.8 g/kg, albino-Swiss mice) and inhibit the Carrageenin oedema of the Wistar rat claw minor than phyenylbutazon and indometacin.