949912-63-4Relevant academic research and scientific papers
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida
Meleddu, Rita,Distinto, Simona,Corona, Angela,Maccioni, Elias,Arridu, Antonella,Melis, Claudia,Bianco, Giulia,Matyus, Peter,Cottiglia, Filippo,Sanna, Adriana,De Logu, Alessandro
, p. 1672 - 1677 (2016)
Cyclohexyliden- and 2-methylcyclohexyliden-hydrazo-4-arylthiazoles were synthesized and tested as antifungal agents. All compounds exhibited minimal inhibitory concentration (MIC) values comparable with those of fluconazole (FLC). Moreover, some compounds
Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp.
Chimenti, Franco,Bizzarri, Bruna,Maccioni, Elias,Secci, Daniela,Bolasco, Adriana,Fioravanti, Rossella,Chimenti, Paola,Granese, Arianna,Carradori, Simone,Rivanera, Daniela,Lilli, Daniela,Zicari, Alessandra,Distinto, Simona
, p. 4635 - 4640 (2008/12/20)
In this paper, we report on the synthesis of a novel series of 2-thiazolylhydrazone derivatives and the influence of the substituents on the thiazole ring on antifungal activity. All synthesized compounds were screened for their in vitro activities agains
