94992-39-9

Basic information

• Product Name: (2S,6S,11S)-6,11-dimethyl-3-prop-2-yn-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol
• CAS NO: 94992-39-9
• Molecular Formula: C₁₇H₂₁NO
• Molecular Weight: 255.3547
• Mol File: 94992-39-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 380.2°C at 760 mmHg
• Flash Point: 178.4°C
• Density: 1.097g/cm³
• Vapor Pressure: 2.53E-06mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: (2S,6S,11S)-6,11-dimethyl-3-prop-2-yn-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,6S,11S)-6,11-dimethyl-3-prop-2-yn-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol(94992-39-9)
• EPA Substance Registry System: (2S,6S,11S)-6,11-dimethyl-3-prop-2-yn-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol(94992-39-9)

Safety Data

• Hazardous Substances Data: 94992-39-9(Hazardous Substances Data)

Upstream product

• 16808-63-2 (+/-)-normetazocine 
• 106-96-7 propargyl bromide 
• 624-65-7 2-propynyl chloride 

Relevant articles and documents

Agonist-antagonist actions and stereoselectivity of optical pairs of some N-substituted α-N-normetazocines

α-(-)-, (+)-, and (±)-N-4-Methylphenyl-, (-)- and (+)-N-cis-3-chloroallyl-, and (-) and (+)-N-propynyl-N-normetazocine (I, II, and III, respectively) have been prepared from α-(-)-, (+)-, and (±)-N-normetazocine (IV) and tested for antinociceptive activity in mice and in morphine-dependent rhesus monkeys. The results obtained with Ia and b somewhat resemble the results obtained with the corresponding phenazocine isomers, whereas those observed with IIa and b more nearly correspond with those reported for (+)- and (-)-N-allyl-N-normetazocine (SKF 10,047; NANM). The propynyl isomers (IIIa and b) display profiles of activity more closely like the corresponding isomers of metazocine. Evidence is considered which suggests that some of the (+)-isomers merit closer scrunity in animal and human studies.