Z-Tyr-Aca-PHA, also known as Z-Tyr-Aca-L-phenylalanine-7-amido-4-methylcoumarin (Z-Tyr-Aca-AMC), is a synthetic peptide substrate commonly used in enzyme assays, particularly for proteases such as cathepsin B and legumain. The compound consists of a Z-protected tyrosine residue, an acetylated alanine residue, a phenylalanine residue, and a 7-amido-4-methylcoumarin (AMC) fluorophore. When the protease cleaves the peptide bond between the phenylalanine and the AMC, the AMC is released, and its fluorescence is detected, allowing for the quantification of enzyme activity. This substrate is widely used in research to study the function and regulation of proteases, as well as in drug discovery efforts targeting these enzymes.

95015-74-0

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Basic information
1. Product Name: Z-Tyr-Aca-PHA
2. Synonyms:
3. CAS NO:95015-74-0
4. Molecular Formula:
5. Molecular Weight: 531.652
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: N/A
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: Z-Tyr-Aca-PHA(CAS DataBase Reference)
10. NIST Chemistry Reference: Z-Tyr-Aca-PHA(95015-74-0)
11. EPA Substance Registry System: Z-Tyr-Aca-PHA(95015-74-0)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 95015-74-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 95015-74-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,0,1 and 5 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 95015-74:
(7*9)+(6*5)+(5*0)+(4*1)+(3*5)+(2*7)+(1*4)=130
130 % 10 = 0
So 95015-74-0 is a valid CAS Registry Number.

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