950182-24-8

Upstream product

• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 98-59-9 p-toluenesulfonyl chloride 
• 532-20-7 D-Ribose 
• 10257-32-6 D-ribose 

Downstream Products

• 176245-06-0 1-O-benzoyl-2,3-O-isopropylidene-5-O-p-toluenesulfonyl-β-D-ribose 
• 449146-83-2 (3S,4R,5S)-4,5-dihydroxy-3-methylhexahydropyridazine 
• 1301240-41-4 (2S,3S,4R,5S)-N-(4-methoxybenzyl)-2-[4-methoxyphenyl]-3,4-O-isopropylidene-5-methylpyrrolidine-3,4-diol 
• 1301240-46-9 (2S,3S,4R,5S)-N-(4-methoxybenzyl)-2-(p-tolyl)-3,4-O-isopropylidene-5-methylpyrrolidine-3,4-diol 
• 1301240-42-5 C₁₅H₂₁NO₃ 
• 1301240-47-0 C₁₅H₂₁NO₂ 
• 1301240-35-6 4-epi-(+)-codonopsinine 
• 1301240-43-6 (2S,3S,4R,5S)-N-methyl-2-[4-methoxyphenyl]-3,4-O-isopropylidene-5-methylpyrrolidine-3,4-diol 
• 1301240-36-7 (2S,3S,4R,5S)-2-[4-methoxyphenyl]-5-methylpyrrolidine-3,4-diol 
• 1301240-37-8 (2S,3S,4R,5S)-2-(p-tolyl)-5-methylpyrrolidine-3,4-diol 
• 1301240-39-0 C₁₆H₂₃NO₄ 
• 1301240-40-3 (1S,2S,3R,4R)-1-(4-methoxybenzylamino)-1-[4-methoxyphenyl]-2,3-O-isopropylidenepentan-2,3-diol 
• 1301240-45-8 (1S,2S,3R,4R)-1-(4-methoxybenzylamino)-1-(p-tolyl)-2,3-O-isopropylidenepentan-2,3-diol 
• 1604816-94-5 (3aR,4R,8S,9aS,9bS)-2,2-dimethyl-8-phenylhexahydro-3aH-[1,3]dioxolo[4,5-c]isoxazolo[2,3-a]pyridin-4-ol 

Relevant academic research and scientific papers

LINKER AND CARRIER FOR SOLID PHASE SYNTHESIS OF NUCLEIC ACID

PROBLEM TO BE SOLVED: To provide a universal linker capable of suppressing generation of a by-product and more efficiently synthesizing DNA or RNA, a carrier (universal support) for solid-phase synthesis of a nucleic acid carrying the linker, and a produc

Synthesis and fucosidase inhibitory study of unnatural pyrrolidine alkaloid 4-epi-(+)-codonopsinine

The total synthesis of enantiopure 4-epi-(+)-codonopsinine was achieved in 10 steps starting from d-ribose as a chiral building block. The key step involved a highly stereoselective nucleophilic addition of a Grignard reagent to a protected ribosylamine.

Design, synthesis and biological activity of azasugar-based CD163 ectodomain shedding inhibitors

A series of metalloproteinase CD163 ectodomain shedding inhibitors based on azasugar hydroxamic acid scaffold has been synthesized. Among the synthesized compounds, the benzyl derivative 4a and the methyl derivative 4f exhibits 66 and 51 % inhibition, res

Synthesis and investigation of L-fuco- and D-glucurono-azafagomine

The new azasugars (3S,4R,5S)-4,5-dihydroxy-3-methylhexahydropyridazine (3, azafucofagomine) and (3S,4R,5R)4,5-dihydroxyhexahydropyridazine-3-carboxylic acid (4, azaglucuronofagomine) were synthesised. Azafucofagomine (3) was made from D-ribose in ten step

1-N-Iminosugars: Potent and selective inhibitors of β-glycosidases

A series of 1-N-iminosugars were synthesized to supply the need for glycosidase inhibitors that are both highly potent and selective for β- glycosidases. Designed on the basis of the transition-state model of the β- glucosidase reaction, these iminosugar

From Carbohydrates to Carbocycles: Radical Routes via Tellurium Derivatives

D-Ribose was transformed to its protected tosylate 15, followed by a Wittig-reaction to give 16 as a 3:1 mixture of the corresponding Z and E isomers.This mixture was then transformed to the anisyltelluride 17 and the latter cyclized in a radical exchange reaction to a mixture of the carbocycles 18a and 18b (in a 17:2 ratio).The major product 18a was then transformed to various chiral cyclopentane derivatives including the cyclopentenone-derivative 23.Various other carbohydrate-based approaches have also been explored.

A VERSATILE AND STEREOSPECIFIC SYNTHESIS OF A DIHYDROXYETHYLENE DIPEPTIDE ISOSTERE OF RENIN INHIBITORS FROM D-RIBOSE

(2S,3R,4S)-2-Amino-1-cyclohexyl-6-methylheptane-3,4-diol, a dihydroxyethylene dipeptide isostere for renin inhibitors, was synthesized from D-ribose stereospecifically.This method can be readily adapted to other dihydroxyethylene isosteres.