950192-44-6

Basic information

• Product Name: 2(S)-[[(2-iodophenyl)amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid
• Synonyms: 2(S)-[[(2-iodophenyl)amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid
• CAS NO: 950192-44-6
• Molecular Weight: 416.259
• Mol File: 950192-44-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(S)-[[(2-iodophenyl)amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2(S)-[[(2-iodophenyl)amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid(950192-44-6)
• EPA Substance Registry System: 2(S)-[[(2-iodophenyl)amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid(950192-44-6)

Safety Data

• Hazardous Substances Data: 950192-44-6(Hazardous Substances Data)

Upstream product

• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 615-43-0 2-iodophenylamine 
• 133010-05-6 tert-butyl 2-(fluorocarbonyl)pyrrolidine-1-carboxylate 

Downstream Products

• 950192-47-9 2(S)-[[(2-(4-pyridyl)phenyl)amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid 
• 950192-59-3 2(S)-[[2-(4'-fluoro(1,1'-biphenyl))amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid 
• 950192-49-1 2(S)-[[2-(3'-chloro(1,1'-biphenyl))amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid 
• 950192-53-7 2(S)-[[2-(4'-chloro(1,1'-biphenyl))amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid 
• 950192-55-9 2(S)-[[2-(3'-fluoro(1,1'-biphenyl))amino]carbonyl]-1-(1,1-dimethylethylester)-1-pyrrolidinecarboxylic acid 

Relevant articles and documents

Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres

A series of IAP antagonists based on thiazole or benzothiazole amide isosteres was designed and synthesized. These compounds were tested for binding to the XIAP-BIR3 and ML-IAP BIR using a fluorescence polarization assay. The most potent of these compound

INHIBITORS OF IAP

The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula (I): wherein Q, X1, X2, Y, Z1, Z2, Z3, Z4, R1, R2, R3, R3', R4, R4', R5, R6, R6' and n are as described herein.