950194-25-9Relevant articles and documents
One-pot synthesis of isoxazolines from aldehydes catalyzed by iodobenzene
Han, Liuquan,Zhang, Bijun,Xiang, Changbin,Yan, Jie
, p. 503 - 509 (2014/03/21)
A convenient one-pot, three-step procedure for the synthesis of isoxazolines starting from aldehydes has been developed involving catalytic cycloaddition between nitrile oxides and alkenes, in which iodobenzene is used as the catalyst for the in situ generation of a hypervalent iodine intermediate. In this approach, the aldehydes are first transformed with hydroxylamine sulfate into aldoximes, which are then oxidized to nitrile oxides by the in situ generated hypervalent iodine intermediate; finally, a 1,3-dipolar cycloaddition between the nitrile oxides and alkenes occurs to provide the isoxazolines in moderate to good yields.
Enantioselective 1,3-dipolar cycloaddition reactions using chiral lanthanide catalysts
Golebiewski, W. Marek,Gucma, Miroslaw
experimental part, p. 1687 - 1693 (2009/09/06)
(Chemical Equation Presented) Regio- and stereoselective 1,3-dipolar cycloaddition of nitrile oxides to internal 2-pentenols, α,β- unsaturated esters and amides catalyzed by R-(+) BINOL-lanthanide complexes affords corresponding 3-aryl-2-isoxazolines with
Chiral ruthenium Lewis acid-catalyzed nitrile oxide cycloadditions
Brinkmann, Yasmin,Madhushaw, Reniguntala J.,Jazzar, Rodolphe,Bernardinelli, Gerald,Kündig, E. Peter
, p. 8413 - 8419 (2008/02/08)
The synthesis of the chiral ligand (R,R)-BIPHOP-F is detailed. Its coordination to a cationic cyclopentadienyl ruthenium fragment generates [Ru (acetone)(R,R)-BIPHOP-F)Cp][SbF6], a transition metal Lewis acid that catalyzes the [3+2] dipolar cy
