950229-08-0Relevant articles and documents
Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors
Wang, Chenglin,Zhu, Mingfei,Lu, Xiuhong,Wang, Hong,Zhao, Weili,Zhang, Xiongwen,Dong, Xiaochun
, p. 3308 - 3320 (2018)
We report herein the design and synthesis of a series of structural modified dimethylpyridazine compounds as novel hedgehog signaling pathway inhibitors. The bicyclic phthalazine core and 4-methylamino-piperidine moiety of Taladegib were replaced with dim