950511-18-9

Upstream product

• 1338697-46-3 2-(2-chlorophenyl)-2,3-dihydro-1H-naphtho [1,8-de] [1,3,2]diazaborinine 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1008097-03-7 2-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4'-methoxy-1,1'-biphenyl 
• 1008097-05-9 2-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-2'-methyl-1,1'-biphenyl 
• 1008097-04-8 2-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4'-acetyl-1,1'-biphenyl 

Relevant academic research and scientific papers

NiCl2(PMe3)2-catalyzed borylation of aryl chlorides

The cross-coupling of aryl chlorides and bis(pinacolato)diboron was achieved using NiCl2(PMe3)2 catalyst in the presence of metal 2,2,2-trifluoroethoxide. The catalyst smoothly provided the desired products regardless of a variety of functional groups and substituted positions.

The method for producing the phenyl boronic acid ester

PROBLEM TO BE SOLVED: To provide a method for producing phenylboronic acid esters in good yield from diborons and aryl halides by using a nickel catalyst and a base. SOLUTION: In the method for producing phenylboronic acid esters represented by general formula (3), wherein A is an ethylene group or the like which may be substituted by a methyl group, R1is a fluorine atom or the like, and m is an integer of 0-5; diborons and a chlorobenzene derivative are reacted with each other by using a trimethylphosphine coordinated nickel catalyst and alkoxides. COPYRIGHT: (C)2013,JPOandINPIT