950522-76-6Relevant academic research and scientific papers
A practical gold-catalyzed route to 4-substituted oxazolidin-2-ones from N-Boc propargylamines
Lee, Eun-Sun,Yeom, Hyun-Suk,Hwang, Ji-Hyun,Shin, Seunghoon
, p. 3503 - 3507 (2007)
Au1-catalyzed cyclization of N-Boc propargylamines into 4-alkylidene oxazolidin-2-ones is described. This modular approach provides access to a variety of nonproteogenic 4-substituted oxazolidinones that are important in asymmetric synthesis an
Synthesis of homochiral propargyl amines from W-(Boc)-tetrahy dro-2#-l,3-oxazines
Rae, Alastair,Castro, Jose L.,Tabor, Alcthca B.
, p. 1943 - 1948 (2007/10/03)
The functionalisation of homochiral N-(Boc)-tetrahydro-2//-l,3-oxazines with the Grignard reagent of (trimethylsilyl)acetylene under Lewis acidic conditions is described. This leads directly to homochiral propargyl amines in good yields, under mild condit
