950580-24-2

Upstream product

• 950580-23-1 (2S,4S)-2,4-bis[(R)-phenyl-((S)-1-phenylethylamino)methyl]pentane-1,5-diol 
• 950580-25-3 (1S,4R,5S,8R)-4,8-diphenyl-3,7-bis((S)-1-phenylethyl)-3,7-diazabicyclo[3.3.1]nonane-2,6-dione 
• 950580-20-8 dimethyl (2S,4S)-2,4-bis{(R)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}glutarate 
• 950580-21-9 dimethyl (2S,4R)-2,4-bis{(R)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}glutarate 
• 950580-22-0 dimethyl (2S,4S)-2,4-bis[(R)-phenyl-((S)-1-phenylethylamino)methyl]glutarate 
• 950580-16-2 methyl 2-{(S)-[N-benzyl-N-((S)-1-phenylethyl)amino]phenylmethyl}acrylate 

Relevant academic research and scientific papers

First asymmetric synthesis of a C2-symmetric 2-endo,6-endo-disubstituted bispidine

The enantioselective synthesis of a C2-symmetric 2-endo,6-endo-disubstituted bispidine (3,7-diazabicyclo[3.3.1]nonane) has been accomplished for the first time. The key step was a Michael addition of the protected β-amino ester methyl (R)-3-{N-