950586-06-8

Basic information

• Product Name: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,3S)-2-tert-butyldimethylsiloxy-3-(4-methoxyphenylamino)-3-phenylpropanoate
• Synonyms: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,3S)-2-tert-butyldimethylsiloxy-3-(4-methoxyphenylamino)-3-phenylpropanoate
• CAS NO: 950586-06-8
• Molecular Weight: 539.831
• Mol File: 950586-06-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,3S)-2-tert-butyldimethylsiloxy-3-(4-methoxyphenylamino)-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,3S)-2-tert-butyldimethylsiloxy-3-(4-methoxyphenylamino)-3-phenylpropanoate(950586-06-8)
• EPA Substance Registry System: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,3S)-2-tert-butyldimethylsiloxy-3-(4-methoxyphenylamino)-3-phenylpropanoate(950586-06-8)

Safety Data

• Hazardous Substances Data: 950586-06-8(Hazardous Substances Data)

Upstream product

• 1613-90-7 4-methoxy-N-[(E)-phenylmethylidene]aniline 
• 2623-23-6 L-menthyl acetate 
• 950586-04-6 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,3S)-2-hydroxy-3-(4-methoxyphenylamino)-3-phenylpropanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 880781-88-4 (3R,4S)-3-tert-butyldimethylsiloxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one 
• 132127-30-1 (3R,4S)-3-<(tert-butyldimethylsilyl)oxy>-4-phenylazetidin-2-one 
• 132127-34-5 (3R,4S)-3-hydroxy-4-phenylazetidin-2-one 

Relevant articles and documents

Asymmetric synthesis of 3-amino-2-hydroxyalkanoates by Mannich reaction of menthyl acetate with imines and subsequent oxidation

Lithium amide-assisted Mannich-type reaction of menthyl acetate-derived lithium enolate with PMP-arylaldimines and subsequent in situ oxidation with oxaziridine gave syn-3-amino-3-aryl-2-hydroxypropanoates with high syn-selectivity and diastereoselectivit