95059-86-2

Usage

Structure

Contains a 1,2,4-triazole ring and a 4-chlorophenoxy group

Usage

Commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and biologically active compounds

Application

Utilized in the field of agricultural chemistry as a fungicide and plant growth regulator

Potential

Has potential applications in the development of new materials and chemical research.

Upstream product

• 288-88-0 1,2,4-Triazole 
• 91171-22-1 1,1-Bis-(4-chlorophenoxy)-3,3-dimethylbut-1-ene 
• 83338-70-9 Toluene-4-sulfonic acid 1-[(4-chloro-phenoxy)-[1,2,4]triazol-1-yl-methyl]-2,2-dimethyl-propyl ester 

Relevant academic research and scientific papers

Eine einfache, selektive Synthese von (Z)-tert-Butylketen-O,N-acetalen durch Phenol/Azol-Austauschreaktion

Melting the ketene O,O-acetals 1 with azoles in the presence of a catalytic amount of a proton acid yields the ketene O,N-acetals 2.The products of this phenol-azol substitution reaction are obtained as their (E/Z)-mixtures with the (Z)-isomers highly pre

A Facile Synthesis of Ketene O,N-Acetals and Ketene O,O-Acetals by Tosylate Elimination

Reaction of the alcohols 4 and 5 with p-toluensulfonyl chloride leads to the sulfonic esters 6 and 7, respectively, which on treatment with potassium tert-butylate easily react to give the ketene O,N-acetals 8 and O,O-acetals 9, respectively.The (E/Z) isomers 8 arising from the elimination reaction of 7 were identified by their 1H-NMR data after X-ray analysis of one of the isomers of 8e.On one example it is shown that the elimination reaction proceeds stereoselectively "anti".