95065-06-8

Usage

Uses

Used in Pharmaceutical Industry:
5,6-Dihydro-2H-cyclopenta[c]pyrrol-4-one is used as a building block for synthesizing various drugs and biologically active compounds. Its unique structure and properties make it a promising candidate for the development of new pharmaceuticals.
Used in Agrochemical Industry:
5,6-Dihydro-2H-cyclopenta[c]pyrrol-4-one is used as a key intermediate in the synthesis of agrochemicals, contributing to the development of new pesticides and other agrochemical products.
Used in Drug Discovery and Development:
5,6-Dihydro-2H-cyclopenta[c]pyrrol-4-one is used as a valuable molecule for drug discovery and development due to its interesting pharmacological activities and potential role in the synthesis of heterocyclic compounds with diverse biological activities.
Used in Synthesis of Heterocyclic Compounds:
5,6-Dihydro-2H-cyclopenta[c]pyrrol-4-one is used as a starting material for the synthesis of heterocyclic compounds with diverse biological activities, expanding its applications in various fields.

Upstream product

• 930-30-3 cyclopent-2-enone 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 10564-55-3 1-isocyanatomethanesulfonyl-4-methyl-benzene 

Relevant academic research and scientific papers

SUBSTITUTED TETRAHYDROCYCLOPENTA[C]PYRROLES, SUBSTITUTED DIHYDROPYRROLIZINES, ANALOGUES THEREOF, AND METHODS USING SAME

The present invention includes novel substituted bicyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infection and/or hepatitis D virus (HDV) infection in a patient.

Tetrahydrocyclopentapyrrole derivative and preparation method therefor

The purpose of the present invention is to provide: a tetrahydrocyclopentapyrrole derivative capable of being used for preventing or treating a peptic ulcer gastritis or reflux esophagitis; a preparation method therefor; and a pharmaceutical composition containing the same.

Tetrahydrocyclopenta[c]pyrrole derivative, preparation method and medical applications thereof

The present invention relates to a class of new tetrahydrocyclopenta[c]pyrrole derivatives represented by a general formula (I) and a preparation method thereof, a pharmaceutical composition containing the derivative, and uses of the tetrahydrocyclopenta[c]pyrrole derivative as the treatment agent, particularly the gastric acid secretion inhibitor and the potassium ion competitive acid blocker (P-CABs). Each substituent in the general formula (I) is defined in the specification. The general formula (I) is defined in the specification.

Synthesis of 3,4-fused cycloalkanopyrroles by 1,3-dipolar cycloaddition

The synthesis of a number of 3,4-fused cycloalkanopyrroles bearing substituents on the cycloalkane ring was accomplished by 1,3-dipolar cycloaddition. The yield of the cyclization appeared to depend on the base-sensitivity of the Michael acceptor, but the method is applicable across a broad range of cyclic α,β-unsaturated ketone esters. Functional group transformations can be undertaken following pyrrole synthesis to increase the diversity of cycloalkanopyrroles accessible by this method. One pyrrole thus made is a diester of a conformationally-constrained analogue of porphobilinogen, the precursor of the natural tetrapyrroles.

CONDUCTING POLYMERS FROM 3,4-DISUBSTITUTED POLYPYRROLES.

Pyrrole derivatives, which were substituted in the 3,4-position by a fused alkyl ring have been synthesized and their electrochemical and electrical properties have been investigated. Compounds with a five, six, seven and twelve membered ring fused to the pyrrole moiety were obtained by means of a 3 plus 2 cycloaddition of tosylmethylisocyanide to an alpha , beta -unsaturated ketone. Electrooxidation in acetonitrile/tetrabutylammonium perchlorate led to the deposition of brittle, black, conducting polymer films on the anode, which could be reversibly reduced and reoxidized. The polypyrrole derivative containing the twelve membered ring showed a strong frequency dependence of the conductivity at 100 K.