950672-64-7

Upstream product

• 950672-60-3 (R)-2-benzylsulfanylmethyl-2-methyl-4-phenyl-oxazolidine 
• 950672-62-5 (R)-3-(benzylthio)-2-methyl-2-((R)-1-phenyl-2-(trimethylsilyloxy)ethylamino)propanenitrile 

Downstream Products

• 950672-66-9 (R)-5-(benzylthiomethyl)-1-((R)-2-hydroxy-1-phenylethyl)-5-methylimidazolidine-2,4-dione 
• 1367363-43-6 methyl (R)-1-amino-3-(benzylthio)-2-methyl-1-oxopropan-2-yl((R)-2-hydroxy-1-phenylethyl)carbamate 
• 459818-49-6 (R)-5-(benzylthiomethyl)-5-methylimidazolidine-2,4-dione 
• 1367363-42-5 (3R,5R)-methyl 3-(benzylthio-methyl)-3-methyl-2-oxo-5-phenylmorpholine-4-carboxylate 

Relevant academic research and scientific papers

Stereoselective synthesis of a dialkylhydantoin featuring an asymmetric Strecker reaction on an acyclic dialkyl ketone

A diastereoselective Strecker reaction using (R)-(-)-phenylglycinol forms the basis of a concise scalemic route to dialkylhydantoin 1. The phenylglycinol functionality was exploited in the manipulation of the aminonitrile Strecker product through to the d

NOVEL CRYSTAL MODIFICATIONS

Novel crystal modifications of (5S)-5-[4-(5-chloro-pyridin-2-yloxy)-piperidine-1-sulfonylmethyl]-5-methyl-imidazolidine-2,4-dione are disclosed together with processes for preparing such modifications, pharmaceutical compositions comprising such a modification, and the use of such a modification in therapy.