950736-05-7 Usage
Uses
Used in Oncology:
BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)is used as a targeted B-Raf inhibitor for the treatment of cancers driven by B-Raf mutations. Its high selectivity for B-Raf over other kinases allows for more precise targeting of cancer cells, potentially reducing side effects and improving treatment outcomes.
Used in Cancer Research:
In the field of cancer research, BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)serves as a valuable tool for studying the role of B-Raf in cancer development and progression. Its ability to selectively inhibit B-Raf activity helps researchers better understand the molecular mechanisms underlying B-Raf-mediated tumor growth and identify potential therapeutic targets.
Used in Drug Development:
BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)is utilized in drug development as a lead compound for the design and synthesis of novel B-Raf inhibitors. Its high potency and selectivity make it an attractive starting point for the development of more effective and safer cancer therapies.
Used in Drug Screening:
In the process of drug screening, BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)is employed as a reference compound to evaluate the activity of newly synthesized compounds against B-Raf. This helps in identifying potential candidates with improved potency, selectivity, and pharmacological properties for further optimization and development.
Check Digit Verification of cas no
The CAS Registry Mumber 950736-05-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,0,7,3 and 6 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 950736-05:
(8*9)+(7*5)+(6*0)+(5*7)+(4*3)+(3*6)+(2*0)+(1*5)=177
177 % 10 = 7
So 950736-05-7 is a valid CAS Registry Number.
950736-05-7Relevant academic research and scientific papers
Pyrazolo[1,5-A]pyrimidine derivatives and methods of use thereof
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Page/Page column 40, (2010/11/28)
The present invention relates to pyrazolo[1,5-a]pyrimidine derivatives, compositions comprising an effective amount of a pyrazolo[1,5-a]pyrimidine derivative and methods for treating or preventing cancer, comprising administering to a subject in need thereof an effective amount of a pyrazolo[1,5-a]pyrimidine derivative.
