950747-14-5Relevant academic research and scientific papers
First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargyl ketone
Matsuda, Masaaki,Yamazaki, Takahiro,Fuhshuku, Ken-ichi,Sugai, Takeshi
, p. 8752 - 8760 (2008/02/10)
While the first total synthesis of modiolide A (1a), a 10-membered ring lactone with a marine-origin was achieved, an important chiral building block for constructing the chirality at C-4 in 1a, (S)-6-[(4-methoxybenzyl)oxy]-1-trimethylsilyl-1-hexyn-3-ol (
