950763-07-2

Basic information

• Product Name: 3-((dimethylamino)methyl)-N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide
• CAS NO: 950763-07-2
• Molecular Weight: 353.421
• Mol File: 950763-07-2.mol

Chemical Properties

• CAS DataBase Reference: 3-((dimethylamino)methyl)-N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((dimethylamino)methyl)-N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide(950763-07-2)
• EPA Substance Registry System: 3-((dimethylamino)methyl)-N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide(950763-07-2)

Safety Data

• Hazardous Substances Data: 950763-07-2(Hazardous Substances Data)

Upstream product

• 133831-28-4 methyl 3-formyl-6-indolecarboxylate 
• 824-94-2 p-methoxybenzyl chloride 
• 950763-33-4 methyl 3-formyl-1-(4-methoxybenzyl)-1H-indole-6-carboxylate 

Relevant articles and documents

Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors

We report the synthesis and evaluation of a class of selective multitarget agents for the inhibition of HDAC6, HDAC8, and HDAC10. The concept for this study grew out of a structural analysis of the two selective inhibitors Tubastatin A (HDAC6/10) and PCI-

INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE

Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the acitivy of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.