950848-26-7Relevant academic research and scientific papers
Enzymatic preparation of an (S)-amino acid from a racemic amino acid
Chen, Yijun,Goldberg, Steven L.,Hanson, Ronald L.,Parker, William L.,Gill, Iqbal,Tully, Thomas P.,Montana, Michael A.,Goswami, Animesh,Patel, Ramesh N.
experimental part, p. 241 - 248 (2011/10/08)
The (S)-amino acid, (S)-2-amino-3-(6-o-tolylpyridin-3-yl)propanoic acid (3), is a key intermediate needed for synthesis of an antidiabetic drug candidate. Three enzymatic routes to 3 were explored. (S)-Amino acid 3 could be prepared in 73% isolated yield
