950848-64-3

Upstream product

• 950848-62-1 C₂₆H₃₃ClN₄O₃ 
• 30766-11-1 5-bromoisonicotinic acid 
• 1359649-44-7 5-bromo-pyridine-2-carboxylic acid hydrochloride 
• 943778-90-3 C₆H₃BrClNO*ClH 
• 950848-57-4 C₁₈H₂₇N₃O₄ 
• 950848-58-5 C₁₈H₂₆BrN₃O₄ 
• 950848-61-0 C₂₄H₃₈N₄O₄ 

Relevant academic research and scientific papers

HETEROCYCLIC SUBSTITUTED PYRIDINE COMPOUNDS WITH CXCR3 ANTAGONIST ACTIVITY

The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prodrug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having the general structure shown in Formula 1: or a pharmaceutically acceptable salt, solvate or ester thereof. Also disclosed is a method of treating chemokine mediated diseases, such as, palliative therapy, curative therapy, prophylactic therapy of certain diseases and conditions such as inflammatory diseases (non-limiting example(s) include, psoriasis), autoimmune diseases (non-limiting example(s) include, rheumatoid arthritis, multiple sclerosis), graft rejection (non-limiting example(s) include, allograft rejection, zenograft rejection), infectious diseases (e.g, tuberculoid leprosy), fixed drug eruptions, cutaneous delayed-type hypersensitivity responses, ophthalmic inflammation, type I diabetes, viral meningitis and tumors using a compound of Formula 1.