951023-78-2Relevant academic research and scientific papers
Novel C2-C3′ N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3′
Larroque, Anne-Laure,Dubois, Joelle,Thoret, Sylviane,Aubert, Genevieve,Guenard, Daniel,Gueritte, Francoise
, p. 4722 - 4726 (2007/10/03)
A series of novel docetaxel analogues possessing a peptide side chain at the C3′-N position was synthesized. These compounds were designed to mimic a region of the α-tubulin loop that is equivalent to the paclitaxel binding pocket in β-tubulin. Eight new
