95110-79-5

Upstream product

• 104354-60-1 cyclohexylchloromethyl phenyl sulfoxide 
• 108-98-5 thiophenol 
• 2719-27-9 cyclohexanylcarbonyl chloride 
• 78358-09-5 40chlorobenzyl methanesulfonate 
• 102104-36-9 2-Benzenesulfinyl-2-chloro-1-(4-chloro-phenyl)-2-cyclohexyl-ethanol 
• 72653-48-6 α-chloroisobutyl phenyl sulfide 
• 13307-61-4 Isobutylthiobenzene 
• 95150-10-0 1,2-epoxy-2-(4-chlorophenyl)-1-cyclohexyl-1-phenylsulfinylethane 

Relevant academic research and scientific papers

Alternative approach toward the generation of benzylic zinc reagent: Direct oxidative addition of active zinc into the carbon-oxygen bond of benzyl mesylates

The use of highly active zinc, prepared by the Rieke method, for the direct preparation of benzylic zinc mesylate was investigated. The oxidative addition of highly active zinc to benzyl mesylate was easily completed under mild conditions. The resulting benzylic zinc mesylates were employed in subsequent cross-coupling reactions with a broad range of electrophiles, and the formation of the corresponding products was successful.

α,β-Epoxy Sulfoxides as Useful Intermediates in Organic Synthesis. I. A Novel Synthesis of Dialkyl Ketones and a Synthesis of Aldehydes from Ketones by One Carbon Elongation

Treatment of α,β-epoxy sulfoxides, prepared from 1-chloroalkyl phenyl sulfoxides with ketones or aldehydes, with sodium benzeneselenolate gives dialkyl ketones or aldehydes in good yields under mild conditions.The mechanism of this reaction and an application of this process to a formal total synthesis of dihydrojasmone are described.

A NOVEL SYNTHESIS OF DIALKYL KETONES AND α-SULFENYLATED CARBONYL COMPOUNDS FROM α,β-EPOXY SULFOXIDES

Treatment of α,β-epoxy sulfoides with excess sodium phenylselenide and various kinds of alkylthiolates gave dialkyl ketones and α-sulfenylated carbonyl compounds, respectively, in good yields under mild conditions.