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3-((6-chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy)-2,6-difluorobenzaMide is a small molecule cell-cycle inhibitor with potent antibacterial properties. It is characterized by its unique chemical structure, which includes a chlorothiazolo[5,4-b]pyridin-2-yl methoxy group and a 2,6-difluorobenzamide moiety. 3-((6-chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy)-2,6-difluorobenzaMide has been found to effectively inhibit bacterial cell division protein FtsZ, making it a promising candidate for the development of new antibacterial agents.

951120-33-5

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951120-33-5 Usage

Uses

Used in Antibacterial Applications:
3-((6-chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy)-2,6-difluorobenzaMide is used as an antibacterial agent for its ability to inhibit bacterial cell division protein FtsZ. This action disrupts the normal cell cycle of bacteria, leading to their growth inhibition and eventual death. Its effectiveness against a range of bacterial species makes it a valuable tool in the fight against antibiotic-resistant infections.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-((6-chlorothiazolo[5,4-b]pyridin-2-yl)Methoxy)-2,6-difluorobenzaMide is used as a lead compound for the development of new antibacterial drugs. Its unique mechanism of action and potential to target antibiotic-resistant bacteria make it an attractive candidate for further research and development. By optimizing its chemical structure and properties, scientists can potentially create more effective and targeted antibacterial agents to combat the growing threat of drug-resistant infections.

Check Digit Verification of cas no

The CAS Registry Mumber 951120-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,1,1,2 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 951120-33:
(8*9)+(7*5)+(6*1)+(5*1)+(4*2)+(3*0)+(2*3)+(1*3)=135
135 % 10 = 5
So 951120-33-5 is a valid CAS Registry Number.

951120-33-5Upstream product

951120-33-5Downstream Products

951120-33-5Relevant academic research and scientific papers

ANTIBACTERIAL AGENTS

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Page/Page column 50; 59, (2010/11/28)

Compounds of formula (I) have antibacterial activity wherein R represents hydrogen or 1, 2 or 3 optional substituents; W is =C(R1)- or =N-; R1 is hydrogen or an optional substituent and R2 is hydrogen, methyl, or fluorine; or R1 and R2 taken together are -CH2-, -CH2CH2-, -O-, or, in either orientation, -O- CH2- Or -OCH2CH2-; R3 is a radical of formula -(Alk1)m-(Z)p-(Alk2)n-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is 1, Z is -O-, -S-, -S(O)-, -S(O2)-, -NH-, -N(CH3)-, -N(CH2CH3)-, -C(=O)-, -O-(C=O)-, -C(=O)-O-, or an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted divalent bicyclic heterocyclic radical having 5 to 10 ring atoms; Alk1 and Alk2 are optionally substituted C1C6 alkylene, C2-C6 alkenylene, or C2-C6 alkynylene radicals, which may optionally terminate with or be interrupted by -O-, -S-, -S(O)-, -S(O2)-, -NH-, -N(CH3)-, or -N(CH2CH3)-; and Q is hydrogen, halogen, nitrile, or hydroxyl or an optionally substituted monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted bicyclic heterocyclic radical having 5 to 10 ring atoms.

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