951345-76-9

Upstream product

• 951327-36-9 C₁₈H₂₃BrO₇ 
• 951327-34-7 C₁₄H₁₅BrO₅ 
• 951327-38-1 (1S,2S,5R,6S)-2-(4-methoxybenzyloxy)-3-bromo-5,6-bis(methoxymethoxy)cyclohex-3-enol 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 951345-77-0 (1S,4R,5R,6R)-2-bromo-4,5,6-tris(methoxymethoxy)cyclohex-2-enol 
• 951345-79-2 (3R,4R,5R,6R)-6-azido-1-bromo-3,4,5-tris(methoxymethoxy)cyclohex-1-ene 
• 951345-78-1 (1S,4R,5R,6S)-2-bromo-4,5,6-tris(methoxymethoxy)cyclohex-2-enyl methanesulfonate 
• 951345-92-9 (1R,4R,5S,6R)-2-bromo-4,5,6-tris(methoxymethoxy)-cyclohex-2-enamine 
• 951345-91-8 N-[(1R,4R,5S,6R)-2-bromo-4,5,6-tris(methoxymethoxy)cyclohex-2-enyl]-2,2,2-trichloroacetamide 
• 951345-89-4 C₁₄H₂₁Cl₃BrNO₇ 
• 951345-80-5 (1R,4R,5R,6R)-2-bromo-4,5,6-tris(methoxymethoxy)cyclohex-2-enamine 

Relevant academic research and scientific papers

Chemoenzymatic approaches to lycorine-type amaryllidaceae alkaloids: Total syntheses of enf-lycoricidine, 3-epi-ent-lycoricidine, and 4-deoxy-3-epi-ent- lycoricidine

The readily available and enzymatically derived cis-1,2-dihydrocatechol 4 has been elaborated, over 11 steps including an Overman rearrangement, into the non-natural enantiomer, (-)-1, of the alkaloid lycoricidine [(+)-1]. Related chemistries have provided analogues 18, 19, and 26.

A chemoenzymatic total synthesis of ent-narciclasine

The synthesis of the title compound [(-)-1] has been achieved, for the first time, by reacting the aryl boronic acid ester 4 with the aminoconduritol derivative 6 under Suzuki-Miyaura cross-coupling conditions then subjecting the product phenanthridinone