951596-00-2

Basic information

• Product Name: N-benzyl-4-(thiophen-3-yl)benzamide
• CAS NO: 951596-00-2
• Molecular Weight: 293.389
• Mol File: 951596-00-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-4-(thiophen-3-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-4-(thiophen-3-yl)benzamide(951596-00-2)
• EPA Substance Registry System: N-benzyl-4-(thiophen-3-yl)benzamide(951596-00-2)

Safety Data

• Hazardous Substances Data: 951596-00-2(Hazardous Substances Data)

Upstream product

• 181132-79-6 4-(thiophen-3-yl)benzoic acid chloride 
• 100-46-9 benzylamine 

Relevant articles and documents

Structural modifications of salicylates: Inhibitors of human CD81-receptor HCV-E2 interaction

Starting point of the present paper was the result of a virtual screening using the open conformation of the large extracellular loop (LEL) of the CD81-receptor (crystal structure: PDB-ID: 1G8Q). After benzyl salicylate had been experimentally validated to be a moderate inhibitor of the CD81-LEL-HCV-E2 interaction, further optimization was performed and heterocyclic-substituted benzyl salicylate derivatives were synthesized. The compounds were tested for their ability to inhibit the interaction of a fluorescence-labeled antibody to CD81-LEL using HUH7.5 cells. No compound showed an increase concerning the inhibition of the protein-protein interaction compared to benzyl salicylate.