BGP 15, also known as a calcipotriene-based vitamin D3 analog, is a compound that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis. It has been studied for its influence on proteasomal degradation of missense dystrophins and has been found to have cardioprotective properties, improve mitochondrial function, protect neurons from dying, and promote cardiac innervation.
951628-79-8
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Basic information
- Product Name: BGP 15
- Synonyms: BGP 15
- CAS NO:951628-79-8
- Molecular Formula: C14H23ClN4O2
- Molecular Weight: 314.81
- EINECS: N/A
- Product Categories: N/A
- Mol File: 951628-79-8.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20°C
- Solubility: DMSO (Slightly), Methanol (Slightly)
- CAS DataBase Reference: BGP 15(CAS DataBase Reference)
- NIST Chemistry Reference: BGP 15(951628-79-8)
- EPA Substance Registry System: BGP 15(951628-79-8)
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Safety Data
- Hazard Codes: Xn
- Statements: 22
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 951628-79-8(Hazardous Substances Data)
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951628-79-8 Usage
Uses
Used in Pharmaceutical Industry:BGP 15 is used as a cardioprotective agent for its ability to protect the heart and improve mitochondrial function.
Used in Neuroprotection:
BGP 15 is used as a neuroprotective agent for its ability to protect neurons from dying both in vitro and in vivo.
Used in DNA Repair and Apoptosis Regulation:
BGP 15 is used as an inhibitor of poly(ADP-ribose) polymerasesis (PARP) for its role in regulating DNA repair and apoptosis.
Used in Dystrophin Research:
BGP 15 is used in the study of its influence on proteasomal degradation of missense dystrophins for better understanding of the protein's role in muscle diseases.
Biochem/physiol Actions
BGP-15 is PARP inhibitor, HSP72 activator.Check Digit Verification of cas no
The CAS Registry Mumber 951628-79-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,1,6,2 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.Calculate Digit Verification of CAS Registry Number 951628-79:
(8*9)+(7*5)+(6*1)+(5*6)+(4*2)+(3*8)+(2*7)+(1*9)=198
198 % 10 = 8
So 951628-79-8 is a valid CAS Registry Number.
951628-79-8Upstream product
951628-79-8Downstream Products
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BGP 15
