951655-67-7

Basic information

• Product Name: trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid tert-butyl ester
• Synonyms: trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid tert-butyl ester
• CAS NO: 951655-67-7
• Molecular Weight: 517.602
• Mol File: 951655-67-7.mol

Chemical Properties

• CAS DataBase Reference: trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid tert-butyl ester(951655-67-7)
• EPA Substance Registry System: trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid tert-butyl ester(951655-67-7)

Safety Data

• Hazardous Substances Data: 951655-67-7(Hazardous Substances Data)

Upstream product

• 619-66-9 4-Carboxybenzaldehyde 
• 35849-02-6 4-[1,3]dioxolan-2-yl-benzoic acid 
• 951655-60-0 (1-benzenesulfonyl-5-methoxy-1H-indol-2-yl)-(4-[1,3]dioxolan-2-yl-phenyl)methanone 
• 951655-56-4 4-[1,3]dioxolan-2-ylbenzoyl chloride 
• 951655-63-3 4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)benzaldehyde 
• 35000-37-4 (tert-butyloxycarbonylmethyl)triphenylphosphonium chloride 

Downstream Products

• 951655-69-9 trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid 
• 951655-78-0 trans-3-[4-(5-methoxy-1H-indole-2-carbonyl)phenyl]-N-(tetrahydropyran-2-yloxy)acrylamide 
• 951655-75-7 trans-3-[4-(1-benzenesulfonyl-5-methoxy-1H-indole-2-carbonyl)phenyl]-N-(tetrahydropyran-2-yloxy)acrylamide 
• 951655-72-4 trans-3-[4-(5-methoxy-1H-indole-2-carbonyl)phenyl]acrylic acid 

Relevant articles and documents

2-Aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors

Histone deacetylase (HDAC) inhibitors are considered to be drugs for targeted cancer therapy and second-generation HDIs are currently being tested in clinical trials. Here, we report on the synthesis and biological evaluation of a novel HDAC inhibitor sca