951657-98-0

Usage

General Description

5-(4'-bromophenyl)-2-pyridinecarbonitrile is a chemical compound with the molecular formula C12H7BrN2. It is a white to off-white solid that is used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical and agrochemical products. The compound has a pyridine ring with a cyano group and a bromophenyl group, which gives it the potential for diverse chemical reactions and applications. It is important to handle 5-(4'-bromophenyl)-2-pyridinecarbonitrile with care, as it is a potentially hazardous substance and should be used in a controlled environment by trained professionals.

Upstream product

• 5467-74-3 4-Bromophenylboronic acid 
• 97483-77-7 2-Cyano-5-bromopyridine 

Downstream Products

• 951658-00-7 phenyl[1,1']phenyl[4',5'']pyridinyl-4,2''-bis-carbonitrile 

Relevant academic research and scientific papers

Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum

A series of azaterphenyl diamidines has been synthesized and evaluated for in vitro antiprotozoal activity against both Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.) and in vivo efficacy in the STIB900 acute mouse model for T

Azaterphenyl diamidines as antileishmanial agents

Eighteen diamidino azaterphenyls and analogues were evaluated as anti-leishmanials; nine of the compounds gave IC50 values less than 1 μM, five exhibited values less than 0.40 μM, and two gave values less than 0.10 μM in a Leishmania donovani a