951781-87-6

Basic information

• Product Name: 2-(4-fluorophenyl)-3-methylthiophene
• Synonyms: 2-(4-fluorophenyl)-3-methylthiophene
• CAS NO: 951781-87-6
• Molecular Weight: 192.257
• Mol File: 951781-87-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-3-methylthiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-3-methylthiophene(951781-87-6)
• EPA Substance Registry System: 2-(4-fluorophenyl)-3-methylthiophene(951781-87-6)

Safety Data

• Hazardous Substances Data: 951781-87-6(Hazardous Substances Data)

Upstream product

• 885692-91-1 4,4,5,5-tetramethyl-2-[3-(methyl)-thiophen-2-yl]-1,3,2-dioxaborolane 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 517867-28-6 2,2-dimethyl-propionic acid 1-ethoxythiocarbonylsulfanyl-4-(4-fluoro-phenyl)-3-methyl-4-oxo-butyl ester 

Relevant articles and documents

Useful thiophene derivatives in the treatment of diabetes

The present invention relates to a thiophene derivative of the following general formula I or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof or to its use as a drug in particular intended for treating and/or preventing diabetes, its complications and/or associated pathologies, advantageously diabetes of type II and hyperglycemia.

Flexible routes to thiophenes

Three convergent routes to thiophenes are described, hinging on the radical addition of α-xanthyl ketones to ethyl vinyl sulfide or to vinyl pivalate. The latter route ultimately proved to be the most versatile and efficient (61-94%).