951892-63-0Relevant academic research and scientific papers
Phosphorus Coordination Chemistry in Catalysis: Air Stable P(III)-Dications as Lewis Acid Catalysts for the Allylation of C-F Bonds
Chitnis, Saurabh S.,Lafortune, James H. W.,Cummings, Haley,Liu, Liu Leo,Andrews, Ryan,Stephan, Douglas W.
supporting information, p. 4540 - 4544 (2019/01/08)
Modification of C-F bonds with main-group catalysts has typically employed electron-deficient Lewis superacids in high oxidation states, and the challenges of preparing and handling such species have prevented broader adoption of metal-free reduction protocols. Here, we show that a hemilabile ligand coordinated to an easily accessed P(III) center imparts air stability without sacrificing the ability to activate C-F bonds. Catalytic C-C coupling of benzyl fluorides with allylsilanes was achieved using a P(III) complex under benchtop conditions. This application of coordination chemistry principles to main-group Lewis acids reveals a new strategy for controlling catalysis.
