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95194-86-8

95194-86-8

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95194-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 95194-86-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,1,9 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 95194-86:
(7*9)+(6*5)+(5*1)+(4*9)+(3*4)+(2*8)+(1*6)=168
168 % 10 = 8
So 95194-86-8 is a valid CAS Registry Number.

95194-86-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 9-benzyl-2-chloro-3H-purin-6-one

1.2 Other means of identification

Product number -
Other names 9-benzyl-2-chloro-3,9-dihydro-6H-purin-6-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95194-86-8 SDS

95194-86-8Downstream Products

95194-86-8Relevant articles and documents

Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: Part 1

Matasi, Julius J.,Brumfield, Stephanie,Tulshian, Deen,Czarnecki, Michael,Greenlee, William,Garlisi, Charles G.,Qiu, Hongchen,Devito, Kristine,Chen, Shu-Cheng,Sun, Youngliang,Bertorelli, Rosalia,Geiss, William,Le, Van-Duc,Martin, Gregory S.,Vellekoop, Samuel A.,Haber, James,Allard, Melissa L.

, p. 3805 - 3808 (2011/07/31)

Structure-activity relationship (SAR) efforts around our initial lead compound 1 led to the identification of potent P2X7 receptor antagonists with improved pharmacokinetic profiles. These compounds were potent and selective at the P2X7 receptor in both human and rodent. Compound (entry 31) exhibited oral efficacy in the rat MIA and CCI pain models.

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