951963-66-9Relevant academic research and scientific papers
New heterocyclic systems based on 1-hydrazino- 5,6,7,8-tetrahydro[2,7] naphthyridine: 7,8,9,10-tetra- hydro[1,2,4]triazolo[3,4-a]- and 7,8,9,10-tetra- hydro[1,2,4]triazolo[5,1-a][2,7]naphthyridines s. n. sirakanyan
Avetisyan,Noravyan
, p. 470 - 475 (2012/10/29)
Methods have been developed for the synthesis of new substituted 7,8,9,10-tetrahydro[1,2,4]triazolo-[3,4-a][2,7]naphthyridines from 3-chloro-1-hydrazino-7-methyl-5,6,7,8-tetrahydro-[2,7]naphthyridine-4- carbonitrile. It was shown that on heating in an amine (ethanolamine, pyrrolidine, 2-hydroxy-propylamine), they undergo a Dimroth rearrangement at the triazole fragment, being converted into 7,8,9,10-tetrahydro[1,2,4]triazolo[5,1- a][2,7]naphthyridine derivatives.
