952021-60-2 Usage
Biochem/physiol Actions
PF-477736 may be effectively used to resensitize platinum resistant ovarian cancer cells. PF-477736 alone or in combination with other chemotherapeutic agents may be used to treat triple-negative breast cancer.
references
[1] blasina a1, hallin j, chen e, arango me, kraynov e, register j, grant s, ninkovic s, chen p, nichols t, o'connor p, anderes k. breaching the dna damage checkpoint via pf-00477736, a novel small-molecule inhibitor of checkpoint kinase 1. mol cancer ther. 2008 aug;7(8):2394-404.
Check Digit Verification of cas no
The CAS Registry Mumber 952021-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,2,0,2 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 952021-60:
(8*9)+(7*5)+(6*2)+(5*0)+(4*2)+(3*1)+(2*6)+(1*0)=142
142 % 10 = 2
So 952021-60-2 is a valid CAS Registry Number.
