952188-00-0 Usage
Uses
Used in Pharmaceutical Industry:
Pioglitazone Impurity is used as a reference material for quality control and analytical testing in the pharmaceutical industry. It helps ensure the purity and potency of Pioglitazone medications, ensuring that they meet regulatory standards and are safe for patients to use.
Used in Research and Development:
Pioglitazone Impurity is also used in research and development for the study of the properties and effects of Pioglitazone. This can help scientists and researchers better understand the drug's mechanism of action, potential side effects, and ways to improve its efficacy and safety.
Used in Regulatory Compliance:
Pioglitazone Impurity is used in regulatory compliance to ensure that pharmaceutical companies adhere to strict guidelines and standards for drug manufacturing. It helps maintain the integrity and quality of medications, protecting patients from potential harm caused by impurities or contamination.
Check Digit Verification of cas no
The CAS Registry Mumber 952188-00-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,2,1,8 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 952188-00:
(8*9)+(7*5)+(6*2)+(5*1)+(4*8)+(3*8)+(2*0)+(1*0)=180
180 % 10 = 0
So 952188-00-0 is a valid CAS Registry Number.
InChI:InChI=1/C28H31N3O3S/c1-3-20-5-9-23(29-18-20)13-15-31-27(32)26(35-28(31)33)17-22-7-11-25(12-8-22)34-16-14-24-10-6-21(4-2)19-30-24/h5-12,18-19,26H,3-4,13-17H2,1-2H3
952188-00-0Relevant academic research and scientific papers
Method for preparing pioglitazone impurity C by one-pot process
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Paragraph 0025; 0026; 0027; 0028; 0029; 0030; 0031-0054, (2017/05/09)
The invention discloses a method for preparing a pioglitazone impurity C by a one-pot process. The method comprises the following step: by using 4-[2-(5-ethyl-2-pyridyl)ethoxy]benzaldehyde, ethyl (5-ethyl-2-pyridyl) methanesulfonate and 2,4-thiazolidinyl dione as raw materials, carrying out reaction by a one-pot process to obtain the pioglitazone impurity C. The method has the advantages of mild reaction conditions, simple technique, short reaction time, fewer byproducts and high yield, and can obtain the high-purity pioglitazone impurity C.
Pioglitazone impurities
Richter, Jindrich,Jirman,Havlicek,Hrdina
, p. 580 - 584 (2008/09/19)
Methods of preparation of API pioglitazone were discussed from the point of view of impurities occurrence. Four real impurities (I-IV) of pioglitazone were prepared and characterized by means of NMR spectroscopy.
