95249-24-4

Basic information

• Product Name: Oxirane, 2,2-dimethyl-3-(1-pentynyl)-3-phenyl-
• CAS NO: 95249-24-4
• Molecular Formula: C15H18O
• Molecular Weight: 214.307
• Mol File: 95249-24-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxirane, 2,2-dimethyl-3-(1-pentynyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxirane, 2,2-dimethyl-3-(1-pentynyl)-3-phenyl-(95249-24-4)
• EPA Substance Registry System: Oxirane, 2,2-dimethyl-3-(1-pentynyl)-3-phenyl-(95249-24-4)

Safety Data

• Hazardous Substances Data: 95249-24-4(Hazardous Substances Data)

Upstream product

• 627-19-0 1-Pentyne 
• 7473-99-6 α-chloroisobutyrophenone 
• 18643-50-0 1-pentynyl lithium 

Relevant articles and documents

Reaction ofα- Halo Ketones with Nucleophiles

p-Nitro- or p-cyanophenacyl chloride or the 1,1-dimethyl derivatives react with the anion of 2-nitropropane to form the C-alkilation product by a radical chain mechanism (SRN1).With the 1,1-dimethyl derivatives, the free radical substitution is photostimulated and occurs in competition with ionic reactions leading to the oxiranes 5 and hydroxy ketones 6.When K+ is used as the counterion, the SRN1 process is favored by complexation with 18-crown-6. p-Nitro-1,1-dimethylphenacyl chloride gives substitution products with diethyl malonate or diethyl mthylmalonate anions via the SRN1 process, but with PhS- or p-MeC6H4SO2-, substitution occurs by competing ionic and radical processes.Propylacetylenide anion reacts to form the oxirane 13a while diethyl phosphite or thiophosphite anions yield the enol phosphate 14a or thiophosphate 14b. 1,1-Dimethylphenacyl chloride reacts by nonradical processes to give the oxirane with acetylenide anions, the substitution products with PhS- or p-MeC6H4SO2- and a mixture of the enol phosphate, and oxirane 16 with diethyl phosphite anion.With Me2C==NO2-K+, mainly the oxirane is formed in Me2SO but mainly substitution via the SRN1 chain is observed in HMPA.