95249-93-7 Usage
Uses
Used in Chemical Research:
Cyclopropyl-1-d1 Methyl-d3 Ketone is used as a research compound for studying chemical reactions and mechanisms. Its isotopically labeled nature allows researchers to track the behavior of specific atoms during reactions, providing valuable insights into reaction pathways and kinetics.
Used in Pharmaceutical Development:
In the pharmaceutical industry, Cyclopropyl-1-d1 Methyl-d3 Ketone serves as a key intermediate in the synthesis of various drug molecules. Its unique structure and isotopically labeled atoms can help in the development of new drugs with improved properties, such as enhanced stability, selectivity, and bioavailability.
Used in Analytical Chemistry:
Cyclopropyl-1-d1 Methyl-d3 Ketone is utilized as a reference material in analytical chemistry for the calibration of instruments and the development of new analytical methods. Its distinct isotopic signature enables accurate measurements and quantification of compounds in complex samples.
Used in Material Science:
In material science, Cyclopropyl-1-d1 Methyl-d3 Ketone can be employed as a building block for the synthesis of novel materials with specific properties. Its cyclopropane ring and deuterated atoms can contribute to the development of materials with unique electronic, optical, or mechanical characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 95249-93-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,2,4 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 95249-93:
(7*9)+(6*5)+(5*2)+(4*4)+(3*9)+(2*9)+(1*3)=167
167 % 10 = 7
So 95249-93-7 is a valid CAS Registry Number.
95249-93-7Relevant academic research and scientific papers
Scope, Limitation, and Mechanism of the Homoconjugate Electrophilic Addition of Hydrogen Halides
Lambert, Joseph B.,Napoli, James J.,Johnson, Katharine Kappauf,Taba, Kalulu N.,Packard, Beverly Sue
, p. 1291 - 1295 (2007/10/02)
Hydrogen halides (HCl, HBr, HI) add by a homoconjugate 1,5 mechanism to cyclopropanes carrying certain electron-withdrawing substituents.When the substituent is COCH3, COC6H5, CO2H, or CN, the reaction gives the 1,3-disubstituted propane in high yield.Addition of DCl gives a product with deuterium only in the position α to the substituent.The order of rates is not in agreement with a mechanism whereby the cyclopropane ring is protonated initially, since the rate of such a process should be slowed by electron-withdrawing groups.The ketones, however, react much more rapidly than benzylcyclopropane, a model for the direct protonation mechanism.The homoconjugate mechanism involves rapid protonation of the side chain, followed by nucleophilic attack on the cyclopropane ring.The reaction is limited to substrates that can be protonated on the side chain to produce an intermediate with charge ajacent to the cyclopropane ring.This charge must be able to be transmitted by resonance to the unsubstituted ring positions in order to facilitate the nucleophilic step.
