952571-15-2Relevant academic research and scientific papers
Dioxane and oxathiane nuclei: Suitable substructures for muscarinic agonists
Piergentili, Alessandro,Quaglia, Wilma,Giannella, Mario,Bello, Fabio Del,Bruni, Bruno,Buccioni, Michela,Carrieri, Antonio,Ciattini, Samuele
, p. 886 - 896 (2007/10/03)
Muscarinic agonists, bearing 1,4-dioxane and 1,4-oxathiane nuclei, were synthesized and tested to evaluate their potency at M1-M4 muscarinic receptor subtypes. The stereochemical relationship between the 2-side chain and the 6-methyl
