952606-63-2Relevant academic research and scientific papers
Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymerase
Hattori, Kouji,Kido, Yoshiyuki,Yamamoto, Hirofumi,Ishida, Junya,Iwashita, Akinori,Mihara, Kayoko
, p. 5577 - 5581 (2007)
A successful design of conformationally restricted novel quinazolinone derivatives linked via a cyclopentene moiety as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors has been developed. One selected member of the new series, 8-chloro-2-[(3S)-3-(4
