95263-04-0Relevant articles and documents
A ratiometric fluorescent probe for magnesium employing excited state intramolecular proton transfer
Singh, Narinder,Kaur, Navneet,Mulrooney, Ray C.,Callan, John F.
, p. 6690 - 6692 (2008)
A simple fluorescent sensor has been developed for the ratiometric recognition of Mg2+ in semi-aqueous solution at pH 7.0. The sensor, a Schiff base, undergoes Excited State Intramolecular Proton Transfer (ESIPT) to generate a keto tautomer with proficient Mg2+ binding capability. The sensor displays good selectivity over other metal ions including alkali/alkali earth ions and can measure Mg2+ ion concentration between 2.0 and 30.0 μM. The binding stoichiometry was established as 2:1 (host:guest) with an association constant (K21) of (1.4 ± 0.1) × 104 M-2. The sensor could potentially be used to detect conditions such as hypermagnesaemia.
Spectroscopic, DNA binding ability, biological activity, DFT calculations and non linear optical properties (NLO) of novel Co(II), Cu(II), Zn(II), Cd(II) and Hg(II) complexes with ONS Schiff base
Abdel Aziz, Ayman A.,Elantabli, Fatma M.,Moustafa,El-Medani, Samir M.
, p. 563 - 576 (2017)
The reaction of Co(II), Cu(II), Zn(II), Cd(II) and Hg(II) with the synthesized N-(2-hydroxy-1-naphthylidene)-2-aminothiophenol Schiff base ligand (H2L) at room temperature resulted in the formation of the five complexes; [Co(HL)2]H2O, 1; [M(HL)2] (M?=?Cu, Zn and Cd), (2–4) and [Hg(HL)Cl], 5. The ligand and its complexes were characterized based on elemental analyses, IR, 1H NMR, magnetic measurement, molar conductance, and thermal analysis. Coats and Redfern method was used to compute the kinetic and thermodynamic parameters. Antimicrobial activities of H2L and its complexes have been studied. The binding of Co(II), Cu(II) and Zn(II) complexes to calf thymus DNA (CT-DNA) has been investigated using UV–Vis and fluorescence absorption spectra. The results indicated that the ligand and its complexes may bind to DNA by intercalation modes, with a much higher binding affinity of the complexes than that of the ligand. The equilibrium geometries of the studied complexes are investigated theoretically at the B3LYP/LANL2DZ level of theory, and it was found that these geometries are non-linear. The calculated EHOMO and ELUMO energies of the studied complexes can be used to calculate the global properties. The calculated nonlinear optical parameters (NLO); first order hyperpolarizibility (β) of the studied complexes show promising optical properties.
Compound with aggregation-induced emission function and preparation method and application thereof
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Paragraph 0052; 0053; 0058-0067, (2021/03/13)
The invention relates to a compound with an aggregation-induced emission function, the chemical structure of the compound is shown as a general formula I, 2-hydroxy-1-naphthaldehyde and 2-aminothiophenol (or 2-aminophenol) react in organic solvents to obtain Schiff base structure intermediates; and recrystallizing and purifying are carried out to obtain the intermediate, and the intermediate is reacted with an oxidant in an organic solvent to obtain the compound with the aggregation-induced emission function. Further the compound is modified to obtain series of functionalized aggregation-induced emission compounds. The synthesis method of the compounds is simple, the reaction conditions are mild, the synthesis is easy, the post-treatment operation is convenient, the yield is high, and theheating reaction shortens the reaction time. The obtained aggregation-induced emission compound has an excited state intramolecular proton transfer effect. Intramolecular weak acting force hydrogen bonds exist between hydroxyl hydrogen atoms on a naphthalene ring and nitrogen atoms on an ortho-benzothiazole ring, an excited state intramolecular proton transfer effect is achieved, and large Stokesshift is shown.
Synthesis, spectroscopic characterization and in vitro studies of new heteroleptic copper (II) complexes derived from 2-hydroxy napthaldehyde Schiff's bases and N, N donor ligands: Antimicrobial, DNA binding and cytotoxic investigations
Kiran, Tummalapalli,Prasanth, Vuppalapati Giri,Balamurali,Vasavi,Munusami, Punnagai,Sathiyanarayanan, Kulathu Iyer,Pathak, Madhvesh
, p. 26 - 34 (2015/05/27)
A series of eight new copper (II) complexes of types [Cu(HL1)(B)] (4a-4d) and [Cu(HL2)(B)] (4e-4h), where HL1 is N-(2-hydroxy-1-naphthalidene)-2-aminophenol, HL2 is N-(2-hydroxy-1-naphthylidene)-2-mercaptoaniline and B is N, N donor ligands viz bipyridyl (bpy), 1,10-phenanthroline (phen), dipyridoquinoxaline (dpq) and dipyridophenazine (dppz) have been synthesized and characterized by elemental analysis as well as by spectroscopic techniques (IR, UV, ESI mass and EPR spectra). The DNA-binding properties of these copper complexes (4a-4h) have been investigated by electronic absorption, viscosity measurements and docking analyses. The results obtained indicated that the complexes get bonded with DNA via an intercalation binding mode with an intrinsic binding constant, Kb (1.116 ± 0.21 to 7.227 ± 0.21) × 104 M-1. The antimicrobial activity assays with the Schiff's bases and their heteroleptic copper (II) complexes of 4a and 4b exhibited profound activity against gram positive bacteria, gram negative bacteria and fungi. Further, complexes 4d and 4h displayed significant cytotoxicity when examined in vitro on a panel of cancerous cell line - human liver cancer cell line - HepG-2 cells (IC50 = 40.82 and 29.74 μg/ml).
Palladium(II) complexes with salicylideneimine based tridentate ligand and triphenylphosphine: Synthesis, structure and catalytic activity in Suzuki-Miyaura cross coupling reactions
Muthu Tamizh, Manoharan,Cooper, Benjamin F.T.,MacDonald, Charles L.B.,Karvembu, Ramasamy
, p. 391 - 400 (2013/03/13)
Square planar palladium(II) complexes of the type [Pd(L)(PPh3)] (1-6) (where L is the dianion of N-(2-mercaptophenyl)salicylideneimine or 5-substituted-N-(2-mercaptophenyl)salicylideneimine or N-(2-mercaptophenyl) naphthylideneimine) have been synthesised from the reactions between [Pd(PPh3)4] and H2L in dichloromethane-ethanol mixture. The new complexes have been characterized by analytical and spectral (electronic, IR, 1H, 13C{1H} and 31P{1H} NMR spectroscopy) techniques. The structures of three complexes (1, 2 and 6) have been solved by single-crystal X-ray diffraction experiments which indicate square planar coordination geometries around palladium(II) by O, N, S and P donor atoms. The palladium(II) complexes (1-6) exhibited good catalytic activity in Suzuki-Miyaura cross-coupling reaction between phenylboronic acid and 4-bromotoluene in N,N-dimethylacetamide at 100 °C. Complex 3 (1 mol%) was found to be the most active and hence was used for probing the scope of possible substrates. Heterocyclic boronic acid and heterocyclic aryl bromides have also been used as substrates to provide heterocyclic biaryls.
Ruthenium(II) carbonyl complexes containing 'pincer like' ONS donor Schiff base and triphenylphosphine as catalyst for selective oxidation of alcohols at room temperature
Muthu Tamizh,Mereiter,Kirchner,Karvembu
body text, p. 194 - 201 (2012/03/11)
Reactions of H2L with [RuHCl(CO)(PPh3)3] in toluene gives [Ru(L)(CO)(PPh3)2] (L = binegative tridentate ONS donor ligand derived from salicylaldehyde/4-substituted salicylaldehyde/2-hydroxy-1-naphthaldehyde and o-aminothiophenol) at room temperature. All the complexes were characterized by elemental analyses and UV-Visible, FT-IR, 1H, 13C and 31P NMR spectroscopic methods. 1H-1H COSY and 1H-31P HMBC spectra of [Ru(L4)(CO)(PPh3) 2] have been studied. 1H-31P HMBC spectrum established the coupling of phosphorus atoms with azomethine proton. The single crystal X-ray analysis of [Ru(L5)(CO)(PPh3)2] revealed that Schiff base ligand is coordinated to the metal center, via dissociation of the two acidic protons, as a dianionic tridentate ONS donor and that ruthenium(II) ion adopts octahedral coordination with the phosphorus atoms in trans-disposition. Ruthenium complexes have been used in conjunction with N-methylmorpholine-N-oxide (NMO) for the catalytic oxidation of various alcohols at room temperature. Benzylic primary and secondary alcohols are oxidized in good to excellent yields, and aliphatic and cyclic alcohols give carbonyl compounds in moderate yields.
Synthesis, characterization and catalytic activity of Fe(III) complexes containing Schiff base and triphenylphosphine ligands
Rani, Sandya,Ramachandra Bhat, Badekai
body text, p. 1289 - 1292 (2011/02/17)
The oxidation of alcohols to carbonyls was investigated by an efficient catalyst system comprising of Fe(III)-Schiff base-triphenylphosphine complex. The complex chloroN-(2-mercaptophenyl)salicylideneiminebis(triphenylphosphine) iron(III) showed higher activity for oxidation of various alcohols under relatively mild conditions.
