952652-02-7

Basic information

• Product Name: (1'S,2S)-2-[(1-methoxy-2,2,2-triphenylethyl)dimethylsiloxy]-1,1,2-triphenylethanol
• Synonyms: (1'S,2S)-2-[(1-methoxy-2,2,2-triphenylethyl)dimethylsiloxy]-1,1,2-triphenylethanol
• CAS NO: 952652-02-7
• Molecular Weight: 634.89
• Mol File: 952652-02-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1'S,2S)-2-[(1-methoxy-2,2,2-triphenylethyl)dimethylsiloxy]-1,1,2-triphenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S,2S)-2-[(1-methoxy-2,2,2-triphenylethyl)dimethylsiloxy]-1,1,2-triphenylethanol(952652-02-7)
• EPA Substance Registry System: (1'S,2S)-2-[(1-methoxy-2,2,2-triphenylethyl)dimethylsiloxy]-1,1,2-triphenylethanol(952652-02-7)

Safety Data

• Hazardous Substances Data: 952652-02-7(Hazardous Substances Data)

Upstream product

• 952651-72-8 (+/-)-(1-methoxy-2,2,2-triphenylethyl)dimethylsilane 
• 108998-83-0 (S)-1,1,2-triphenyl-1,2-ethanediol 
• 42365-04-8 triphenylacetaldehyde 
• 952651-71-7 (+/-)-(1-methoxy-2,2,2-triphenylethyl)(phenyl)dimethylsilane 

Downstream Products

• 952652-04-9 (+)-(S)-(1-methoxy-2,2,2-triphenylethyl)dimethylsilane 

Relevant articles and documents

More than a protective group: Synthesis and applications of a new chiral silane

Enantiomerically pure (-)-(R)- and (+)-(S)-(1-methoxy-2,2,2-triphenylethyl) dimethylsilanes (MOTES-H) were synthesized from triphenylacetaldehyde in five synthetic steps and with 60% overall yield. MOTES-protected α- and β-hydroxycarbonyl compounds were used in Grignard and Diels Alder reactions in the presence of MgBr2 to afford addition products with 87-98% yield and selectivities of up to >120:1 dr. With this method, the pine beetle pheromone (-)-frontalin (67%, 98.5% ee) and naturally occurring (-)-(R)-octane-1,3-diol (90%, >99% ee) were synthesized.