952652-86-7Relevant academic research and scientific papers
Lipopeptide with a RGDK tetrapeptide sequence can selectively target genes to proangiogenic α5β1 integrin receptor and mouse tumor vasculature
Pramanik, Dipankar,Majeti, Bharat K.,Mondal, Goutam,Karmali, Priya P.,Sistla, Ramakrishna,Ramprasad, Obula G.,Srinivas, Gunda,Pande, Gopal,Chaudhuri, Arabinda
supporting information; experimental part, p. 7298 - 7302 (2009/11/30)
Integrins, the major class of αβ heterodimeric transmembrane glycoprotein receptors, play crucial roles in mediating tumor angiogenesis. Genetic ablation experiments combined with use of antibodies/peptide ligands for blocking either α5 or βsu
