95266-21-0Relevant articles and documents
Reduction of Cyclopropanecarboxylic Acids by Borane, a Chemoselective Reaction Sensitive to Steric Interactions and Reaction Conditions
Sydnes, Leiv K.,Pereira, Paula F. F.,Sandberg, Marcel,Oevreboe, Hans H.
, p. 464 - 474 (2007/10/03)
A number of cyclopropanecarboxylic acids have been reduced by borane in tetrahydrofuran to the corresponding cyclopropyl alcohols. The yield was sensitive to the steric influence of the substituents attached to the ring, the reaction temperature, and the
Preparation of Various 1,1-Dihalo-2-haloalkylcyclopropanes and 1,1,2-Trihalocyclopropanes and their Reduction to Dihalides using Tributyltin Hydride
Pettersen, Anita,Jorgensen, Evy,Sydnes, Leiv K.
, p. 603 - 609 (2007/10/02)
The title compounds, most of which were obtained by dihalocarbene addition to the corresponding alkenes, are generally reduced to dihalides in good yields. 1,1-Dichloro-2-chloromethyl-2-methylcyclopropane and all the tribromides investigated are attacked regioselectively at the gem-dihalo moiety, yielding isomeric mixtures of 1-halo-2-haloalkylcyclopropanes.Trihalides containing both bromo and chloro substituents are always attacked at the C-Br bond; as a consequence substituted 2-bromomethyl-1,1-dichlorocyclopropanes undergo ring opening and form 4,4-dichloro-1-butene derivatives.