95273-59-9Relevant academic research and scientific papers
ENANTIOSPECIFIC SYNTHESIS OF THE IMMUNOPOTENTIATORS erythro-9 (2-HYDROXY-3-NONYL) HYPOXANTHINES AND THE threo-DIASTEREOMERS.
Bessodes, M.,Abushanab, E.,Antonakis, K
, p. 5899 - 5902 (2007/10/02)
The title compounds were prepared enantiospecifically by kinetic resolution of (+/-) 1-nonene-3-ol via Sharpless oxidation.The products 1,2R-epoxy-nonane-3S-ol and 1-nonene-3R-ol were efficiently converted to all four stereoisomers of 2-hydroxy-3-nonylamine, which were subsequently incorporated into the target hypoxanthines to evaluate their immunopotentiating activity.
