95291-76-2Relevant articles and documents
Synthesis and in vitro evaluation of novel liver X receptor agonists based on naphthoquinone derivatives
Nishioka, Tatsuma,Endo-Umeda, Kaori,Ito, Yuki,Shimoda, Akane,Takeuchi, Atsuko,Tode, Chisato,Hirota, Yoshihisa,Osakabe, Naomi,Makishima, Makoto,Suhara, Yoshitomo
, (2019/12/04)
We aimed to synthesize novel liver X receptor (LXR) agonists with potent agonist activity and subtype selectivity. Our synthetic scheme started with naphthoquinone derivatives, such as menadione and 2,3-dichloro-1,4-naphthoquinone. We introduced different