953039-29-7

Usage

Uses

Used in Pharmaceutical Industry:
(2-amino-5-bromo-3-chlorophenyl)methanol is used as an intermediate in the synthesis of pharmaceuticals for its versatile chemical properties and ability to be incorporated into various drug molecules.
Used in Agrochemical Industry:
(2-amino-5-bromo-3-chlorophenyl)methanol is used as an intermediate in the synthesis of agrochemicals to develop new compounds for agricultural applications.
Used in Heterocyclic Compound Synthesis:
(2-amino-5-bromo-3-chlorophenyl)methanol is used as a building block in the synthesis of diverse heterocyclic compounds, which have potential applications in various fields such as pharmaceuticals, materials science, and chemical research.
Used in Pharmacological Research:
(2-amino-5-bromo-3-chlorophenyl)methanol is used as a pharmacological agent in research studies due to its biological activity and potential to inhibit certain enzyme pathways in the human body, which may lead to the development of new therapeutic agents.

Upstream product

• 77820-58-7 methyl 3-chloroanthranilate 
• 58026-21-4 2-amino-5-bromo-3-chloro-benzoic acid 
• 6388-47-2 2-amino-3-chlorobenzoic acid 
• 953039-28-6 2-amino-5-bromo-3-chlorobenzoic acid hydrobromide 

Downstream Products

• 1036755-78-8 6-bromo-8-chloroquinazolin-2-ol 

Relevant academic research and scientific papers

KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO

Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: (I) wherein X, Y, R1, R2, R4, R5 R6, R7, R8 and R11 are as defined herein.

A new and deoxidization of the related substance detection method of preparation

The invention provides a method for detecting related substances in bromhexine hydrochloride and preparations of bromhexine hydrochloride, the contents of the main impurity Ia or impurities Ib in bromhexine hydrochloride and the preparations of bromhexine hydrochloride are determined and are used as reference substances to be applied in the determination of impurities in bromhexine hydrochloride and thus the quality of bromhexine hydrochloride and the preparations of bromhexine hydrochloride can be favorably controlled and improved and the administration safety of patients can be improved.

INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR

Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

QUINAZOLINES FOR PDK1 INHIBITION

The invention provides novel quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.